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The Oratorio di San Lorenzo is a small chapel renowned for the extraordinary white stucco decorations by Giacomo Serpotta, transforming every surface into theatrical Baroque tableaux. It was also once home to Caravaggio's Nativity with St Francis and St Lawrence, stolen in 1969 and never recovered.
The Franciscan oratory was built in the 16th century. Giacomo Serpotta decorated it between 1699 and 1707. Caravaggio painted the altarpiece during his brief stay in Palermo in 1609.