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Panagia Acheiropoietos ("Virgin Made Without Hands") is a 5th-century basilica and one of the oldest churches in continuous use in Greece. Its original Roman columns, carved marble capitals, and mosaic fragments make it an invaluable example of early Christian architecture.
Built between 450 and 470 AD, the basilica takes its name from a supposedly miraculous icon. Under Ottoman rule it was the first church in Thessaloniki to be converted into a mosque (1430).